microcirculationРегионарное кровообращение и микроциркуляцияRegional blood circulation and microcirculation1682-66552712-9756Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1682-6655-2022-21-1-12-17microcirculation-1035Research ArticleОБЗОРЫREVIEWSРоль микроциркуляции костной ткани в ее жизнедеяльности и репаративной регенерации. Современные методы неинвазивного исследованияBone tissue microcirculation’s role in its life and repair regeneration. Modern methods of non-invasive researchhttps://orcid.org/0000-0001-5582-5200КрупаткинА. И.KrupatkinA. I.

Крупаткин Александр Ильич – д-р мед. наук, профессор,врач-невролог

127299, Россия, Москва, ул. Приорова, д. 10

10, Priorova str., Moscow, Russia, 127299

ale.ale02@yandex.ruhttps://orcid.org/0000-0003-3263-0755ДорохинА. И.DorokhinA. I.

Дорохин Александр Иванович – д-р мед. наук, зав. кафедрой травматологии и ортопедии

SPIN: 1306-1729

127299, Россия, Москва, ул. Приорова, д. 10

10, Priorova str., Moscow, Russia, 127299

a.i.dorokhin@mail.ruhttps://orcid.org/0000-0002-4675-4313АдриановаА. А.AdrianovaA. A.

Адрианова Анастасия Александровна – травматологортопед, аспирант кафедры травматологии и ортопедии

127299, Россия, Москва, ул. Приорова, д. 10

10, Priorova str., Moscow, Russia, 127299

nastyaloseva@yandex.ruФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр травматологии и ортопедии имени Н. Н. Приорова» Министерства здравоохранения Российской ФедерацииРоссияN. N. Priorov National Medical Research Center of Traumatology and OrthopedicsRussian Federation2022110420222111217Copyright © Крупаткин А.И., Дорохин А.И., Адрианова А.А., 20222022Крупаткин А.И., Дорохин А.И., Адрианова А.А.Krupatkin A.I., Dorokhin A.I., Adrianova A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.microcirc.ru/jour/article/view/1035

Кровоснабжение костной ткани является одним из ключевых факторов в жизнедеятельности и репаративной регенерации костной ткани. Кровотоком осуществляется доставка питательных веществ и кислорода, выводятся токсические вещества. Репаративная регенерация невозможна без участия микроциркуляторного русла костной ткани, преимущественно надкостницы и питающих артериол. Таким образом, исследование микроциркуляции костной ткани позволяет оценить физиологическое состояние костной ткани при норме и патологии, а также динамику консолидации костных отломках при переломах. Ввиду морфологических особенностей костной ткани и ее кровоснабжения, существуют определенные трудности исследования микроциркуляции в режиме реального времени и без оперативного вмешательства. Однако существуют методы, использующие оптические системы ближнего инфракрасного диапазона, которые позволяют выполнять обследование пациентов неинвазивно. В данном обзоре подробно рассмотрены наиболее известные оптические методы, а также не менее эффективный метод ультразвуковой допплерографии.

Blood supply of bone tissue is one of the key factors in vital functions and reparative regeneration. The bloodstream supply nutrients and oxygen, remove toxic substances. Reparative regeneration is not impossible without the participation of the microvasculature of the bone tissue, mainly of the periosteum and feeding arterioles. Thus, the study of the microcirculation of bone tissue makes it possible to evaluate the physiological state of the bone tissue in normal and pathological conditions, as well as the dynamics of the consolidation of the bone fragments in fractures. Considering the morphological features of the bone tissue and its blood supply, there are certain obstacles in the study of microcirculation in real time and without surgery intervention. However, there are exist methods using near-infrared optical systems wich allow to realize a non-invasive examination of patients. This review discusses in detail the most well-known optical methods and also effective method of ultrasound dopplerography.

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The authors declare that there are no conflicts of interest present.