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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microcirculation</journal-id><journal-title-group><journal-title xml:lang="ru">Регионарное кровообращение и микроциркуляция</journal-title><trans-title-group xml:lang="en"><trans-title>Regional blood circulation and microcirculation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-6655</issn><issn pub-type="epub">2712-9756</issn><publisher><publisher-name>Academician I.P. Pavlov First St. Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1682-6655-2023-22-1-110-115</article-id><article-id custom-type="elpub" pub-id-type="custom">microcirculation-1164</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВЫЕ МЕТОДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEW METHODS</subject></subj-group></article-categories><title-group><article-title>Программно-аппаратный комплекс для оценки церебральной ауторегуляции в режиме реального времени</article-title><trans-title-group xml:lang="en"><trans-title>Software and hardware platform for real time evaluation of cerebral auto-regulation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9248-9821</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенютин</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenyutin</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенютин Владимир Борисович – д-р биол. наук, профессор, зав. НИЛ патологии мозгового кровообращения</p><p>197341, Санкт-Петербург, ул. Аккуратова, д. 2</p></bio><bio xml:lang="en"><p>Semenyutin Vladimir B. – doctor of biological sciences, professor, head of the research laboratory of cerebrovascular pathology</p><p>2, Akkuratova str., Saint Petersburg, 197341</p></bio><email xlink:type="simple">lbcp@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1026-8727</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антонов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Antonov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антонов Валерий Иванович – д-р техн. наук, профессор, зав. кафедрой высшей математики</p><p>195251, Санкт-Петербург, ул. Политехническая, д. 29</p></bio><bio xml:lang="en"><p>Antonov Valeriy I. – doctor of technical sciences, professor, head of the department of higher mathematics</p><p>29, Politehnicheskaya str., Saint Petersburg, 195251</p></bio><email xlink:type="simple">antonov_vi@spbstu.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7452-0944</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Веснина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vesnina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Веснина Анастасия Андреевна – младший научный сотрудник НИЛ патологии мозгового кровообращения</p></bio><bio xml:lang="en"><p>Vesnina Anastasiya A. – Junior Researcher, Research Laboratory of Cerebral Circulation Pathology</p><p>29, Politehnicheskaya str., Saint Petersburg, 195251</p></bio><email xlink:type="simple">anastasya.vesnina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1026-8727</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малыхина</surname><given-names>Г. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Malykhina</surname><given-names>G. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малыхина Галина Федоровна – д-р техн. наук, профессор, профессор высшей школы киберфизических систем и управления</p><p>195251, Санкт-Петербург, ул. Политехническая, д. 29</p></bio><bio xml:lang="en"><p>Malykhina Galina F. – Doctor of Technical Sciences, Professor, Professor of the Higher School of Cyber-Physical Systems and Control</p><p>29, Politehnicheskaya str., Saint Petersburg, 195251 </p></bio><email xlink:type="simple">g_f_malychina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2617-6739</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никифорова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikiforova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никифорова Анна Александровна – канд. мед. наук, старший научный сотрудник нИл патологии мозгового кровообращения</p><p>197341, Санкт-Петербург, ул. Аккуратова, д. 2</p></bio><bio xml:lang="en"><p>Nikiforova Anna A. – Senior Researcher, Research Laboratory of Cerebral Circulation Pathology, PhD</p><p>2, Akkuratova str., Saint Petersburg, 197341</p></bio><email xlink:type="simple">nkfrv_a@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0983-1831</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панунцев</surname><given-names>Г. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Panuntsev</surname><given-names>G. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панунцев Григорий Константинович – канд. мед. наук, старший научный сотрудник нИл патологии мозгового кровообращения</p><p>197341, Санкт-Петербург, ул. Аккуратова, д. 2</p></bio><bio xml:lang="en"><p>Panuntsev Grigory K. – Senior Researcher, Research Laboratory of Cerebral Circulation Pathology, PhD</p><p>2, Akkuratova str., Saint Petersburg, 197341</p></bio><email xlink:type="simple">gpanun@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3115-207X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сальников</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Salnikov</surname><given-names>V. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сальников Вячеслав Юрьевич – канд. техн. наук, доцент высшей школы киберфизических систем и управления</p><p>195251, Санкт-Петербург, ул. Политехническая, д. 29</p></bio><bio xml:lang="en"><p>Salnikov Vyacheslav Yu. – Candidate of Technical Sciences, Associate Professor of the Higher School of Cyber-Physical Systems and Control</p><p>29, Politehnicheskaya str., Saint Petersburg, 195251</p></bio><email xlink:type="simple">zvs@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Санкт-Петербургский политехнический университет Петра Великого»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peter the Great St. Petersburg Polytechnic University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>05</day><month>04</month><year>2023</year></pub-date><volume>22</volume><issue>1</issue><fpage>110</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенютин В.Б., Антонов В.И., Веснина А.А., Малыхина Г.Ф., Никифорова А.А., Панунцев Г.К., Сальников В.Ю., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Семенютин В.Б., Антонов В.И., Веснина А.А., Малыхина Г.Ф., Никифорова А.А., Панунцев Г.К., Сальников В.Ю.</copyright-holder><copyright-holder xml:lang="en">Semenyutin V.B., Antonov V.I., Vesnina A.A., Malykhina G.F., Nikiforova A.A., Panuntsev G.K., Salnikov V.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.microcirc.ru/jour/article/view/1164">https://www.microcirc.ru/jour/article/view/1164</self-uri><abstract><p>В настоящее время для неинвазивной оценки состояния церебральной ауторегуляции используются системы обработки данных после проведения исследования, требующие значительного времени (от 2 до 3 часов), необходимого для снятия, преобразования и обработки данных. Актуальность разработки систем для оценки состояния церебральной ауторегуляции в режиме реального времени связана с необходимостью сокращения времени обработки данных, получения результата и возможностью проводить регистрацию ее показателей в динамике при проведении функциональных тестов и мониторингов при лечении пациентов в палатах интенсивной терапии. Разработан программно-аппаратный комплекс для неинвазивной оценки церебральной ауторегуляции у человека в режиме реального времени, основанной на непрерывной регистрации сдвига фаз между линейной скоростью кровотока в артериях основания мозга и системного артериального давления с помощью Фурье и вейвлет-преобразования в диапазоне волн Майера. Программноаппаратный комплекс показал свою эффективность и информативность при стандартизированных нагрузках и может быть использован для диагностики состояния церебральной ауторегуляции в режиме реального времени у больных и для изучения механизмов регуляции мозгового кровотока у здоровых добровольцев.</p></abstract><trans-abstract xml:lang="en"><p>Data processing systems for non-invasive evaluation of cerebral autoregulation are time-consuming and take 2–3 hours to collect, convert and process the data. Development of systems of real-time evaluation of cerebral autoregulation seems to be critical to reduce the time of data processing, obtaining results and to monitor its parameters in functional tests and monitoring the treatment of patients in intensive care units. The developed software and hardware platform of real-time non-invasive evaluation of cerebral autoregulation based on continuous recording of the phase shift between the linear blood flow velocity in the arteries at the base of the brain and systemic arterial pressure uses Fourier and wavelet transform in the Mayer wave range. The hardware-software complex was shown to be effective and informative under standardized loads and can be used to real-time diagnose the state of cerebral autoregulation and to study the mechanisms of regulation of cerebral blood flow in healthy volunteers.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>церебральная ауторегуляция</kwd><kwd>программно-аппаратный комплекс</kwd><kwd>мониторинг в режиме реального времени</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cerebral autoregulation</kwd><kwd>software and hardware complex</kwd><kwd>real-time monitoring</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Источник финансирования: средства гранта РФФИ 19-29-01190.</funding-statement><funding-statement xml:lang="en">This study was sponsored by Russian Foundation for Basic Research grant 19-29-01190.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ortega-Gutierrez S., Peterson N., Masurkar A. et al. 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DOI: 10.1213/01.ane. 0000295802.89962.13.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
