microcirculationРегионарное кровообращение и микроциркуляцияRegional blood circulation and microcirculation1682-66552712-9756Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1682-6655-2024-23-4-5-21microcirculation-1371Research ArticleОБЗОРЫREVIEWSСовременные методы оценки микроциркуляцииCurrent methods for microvascular blood flow researchhttps://orcid.org/0000-0002-2624-6450ВласоваТ. И.VlasovaТ. I.

Власова Татьяна Ивановна – д-р мед. наук, профессор, зав. кафедрой нормальной и патологической физиологии

430000, г. Саранск, ул. Большевистская, д. 68

Vlasova Tatyana I. – MD, Professor; Head, Department of Normal and Pathological Physiology

68, Bol’shevistskaya str., Saransk, 430000

vlasova-t.i@mrsu.ruhttps://orcid.org/0000-0002-6951-7599ВласовТ. Д.VlasovaT. D.

Власов Тимур Дмитриевич – д-р мед. наук, профессор, зав. кафедрой патофизиологии с курсом клинической патофизиологии

197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8

Vlasov Timur D. – MD, Professor, Head, Department of Pathophysiology (with a Course of Clinical Pathophysiology)

6-8, L’va Tolstogo str., Saint Petersburg, 197022

tvlasov@yandex.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Национальный исследовательский Мордовский государственный университет имени Н. П. Огарева»РоссияNational Research Mordovia State UniversityRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской ФедерацииРоссияPavlov UniversityRussian Federation202403012025234521Copyright © Власова Т.И., Власов Т.Д., 20242024Власова Т.И., Власов Т.Д.Vlasova Т.I., Vlasova T.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.microcirc.ru/jour/article/view/1371

Интерес к изучению микроциркуляции тканей как с позиции исследователя, так и клинического специалиста определяется ролью микроциркуляторных нарушений в формировании и прогрессировании патологии, а также возможностью использования полученных данных для диагностики и контроля лечения заболеваний. Дизрегуляция и нарушения структурно-функциональных характеристик микроциркуляторного русла являются звеном патогенеза большинства известных патологических процессов и состояний. В настоящее время существует большое количество методов, позволяющих исследовать особенности микроциркуляции в норме и патологии. В обзоре приведены сведения о наиболее распространенных современных нерадиологических способах изучения микрогемодинамики. Рассмотрены варианты, основные принципы, достоинства и ограничения отдельных методов, базирующихся на принципах плетизмографии, допплерографии, изменении оптических свойств ткани. Также отмечены основные современные тренды совершенствования подходов к изучению микроциркуляции.

Interest in studying tissue microcirculation both from a researcher and a clinical specialist perspective is determined by the role of microcirculatory disorders in the development and progression of pathology and the possibility of using the obtained data to diagnose and control the disease treatment. Disorders of regulation and the structural and functional characteristics of the microcirculatory vessels are a link in the pathogenesis of most known pathological processes and conditions. Currently, there are a large number of methods that allow us to study the features of microvascular blood flow in norm and pathology. The review provides information on the most common modern non-radiological methods for microvascular blood flow research. We discuss the options, basic principles, advantages and limitations of individual methods based on the principles of plethysmography, Dopplerography, and changes in the optical properties of the tissue. Major trends in the improvement of approaches to the study of microcirculation are also noted.

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The authors declare that there are no conflicts of interest present.