microcirculationРегионарное кровообращение и микроциркуляцияRegional blood circulation and microcirculation1682-66552712-9756Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1682-6655-2018-17-3-23-32microcirculation-197Research ArticleОБЗОРЫREVIEWSОптическая неинвазивная диагностика функционального состояния микроциркуляторного русла пациентов с нарушением периферической микрогемодинамикиOptical noninvasive diagnostics of the functional state of microcirculatory bed in patients with disorders of peripheral haemodynamicsЖаркихЕ. В.ZharkikhE. V.ev.zharkikh@gmail.comМаковикИ. Н.MakovikI. N.irina.makovik@gmail.comПотаповаЕ. В.PotapovaE. V.potapova_ev_ogu@mail.ruДрёминВ. В.DreminV. V.dremin_viktor@mail.ruЖеребцовЕ. А.ZherebtsovE. A.zherebzow@gmail.comЖеребцоваА. И.ZherebtsovaA. I.zherebtsova@yandex.ruДунаевА. В.DunaevA. V.inohvat@yandex.ruСидоровВ. В.SidorovV. V.victor.v.sidorov@gmail.comКрупаткинА. И.KrupatkinA. I.aikrup@mail.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Орловский государственный университет имени И. С. Тургенева»РоссияFederal State Budgetary Educational Institution of Higher Education «Orel State University named after I. S. Turgenev»Russian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Орловский государственный университет имени И. С. Тургенева»; Aston UniversityРоссияFederal State Budgetary Educational Institution of Higher Education «Orel State University named after I. S. Turgenev»; Aston UniversityRussian FederationOOO НПП «ЛАЗМА»РоссияSPE «LAZMA» Ltd., MoscowRussian FederationФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр травматологии и ортопедии имени Н. Н. Приорова» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Higher Education «N. N. Priorov National Medical research center of traumatology and orthopaedics» of Ministry of Healthcare of the Russion FederationRussian Federation2018300920181732332Copyright © Жарких Е.В., Маковик И.Н., Потапова Е.В., Дрёмин В.В., Жеребцов Е.А., Жеребцова А.И., Дунаев А.В., Сидоров В.В., Крупаткин А.И., 20182018Жарких Е.В., Маковик И.Н., Потапова Е.В., Дрёмин В.В., Жеребцов Е.А., Жеребцова А.И., Дунаев А.В., Сидоров В.В., Крупаткин А.И.Zharkikh E.V., Makovik I.N., Potapova E.V., Dremin V.V., Zherebtsov E.A., Zherebtsova A.I., Dunaev A.V., Sidorov V.V., Krupatkin A.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.microcirc.ru/jour/article/view/197

Рассмотрены возможности и перспективы применения оптических неинвазивных диагностических технологий для выявления и оценки степени тяжести микроциркуляторных и метаболических нарушений при ревматических заболеваниях и сахарном диабете. Проведены экспериментальные исследования с участием 137 условно здоровых добровольцев и 147 пациентов с указанными заболеваниями (77 пациентов с ревматическими заболеваниями и 70 - с сахарным диабетом). В работе показано, что применение методов лазерной допплеровской флоуметрии, флуоресцентной спектроскопии и спектроскопии диффузного отражения имеет важное диагностическое значение для выявления возникающих нарушений, и данные методы могут быть использованы в качестве дополнительных диагностических способов в арсенале практикующего врача в области ревматологии и эндокринологии.

The possibilities and prospects of optical non-invasive diagnostic technologies for detecting and assessing the severity of microcirculatory and metabolic disorders in rheumatic diseases and diabetes mellitus were assessed. Experimental studies were conducted with the participation of 137 conditionally healthy volunteers and 147 patients with mentioned diseases (77 patients with rheumatic diseases and 70 patients with diabetes). It is shown that the application of laser Doppler flowmetry, fluorescence spectroscopy and diffuse reflectance spectroscopy is of great diagnostic importance for identifying emerging disorders, and these methods can be used as additional diagnostic methods in the arsenal of a practicing physician in the field of rheumatology and endocrinology.

лазерная допплеровская флоуметрияспектроскопия диффузного отраженияфлуоресцентная спектроскопиясахарный диабетревматические заболеванияlaser Doppler flowmetrydiffuse reflectance spectroscopyfluorescence spectroscopydiabetes mellitusrheumatic diseasesReferencesБондаренко О. Н., Аюбова Н. Л., Галстян Г. Р., Дедов И. И. Транскутанная оксиметрия в динамическом наблюдении за пациентами с сахарным диабетоми критической ишемией нижних конечностей // Сахарный диабет. - 2013. - Т 16. - № 1. - С. 33-42. [Bondarenko ON, Ayubova NL, Galstyan GR, Dedov II. Transcutaneous oximetry monitoring in patients with type 2 diabetes mellitus and critical limb ischemia. Diabetes mellitus. 2013;16(1):33-42 (In Russ.)]. doi: 10.14341/2072-0351-3594.Бондаренко О. Н., Аюбова Н. Л., Галстян Г. Р., Дедов И. И. Транскутанная оксиметрия в динамическом наблюдении за пациентами с сахарным диабетоми критической ишемией нижних конечностей // Сахарный диабет. - 2013. - Т 16. - № 1. - С. 33-42. 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The authors declare that there are no conflicts of interest present.