microcirculationРегионарное кровообращение и микроциркуляцияRegional blood circulation and microcirculation1682-66552712-9756Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1682-6655-2018-17-4-11-23microcirculation-256Research ArticleОБЗОРЫREVIEWSМатематические модели в сердечно-сосудистой системе человека. Подходы к описанию колебаний с частотой 0,1 Гц вариабельности ритма сердца и магистрального кровотокаMathematical models in the human cardiovascular system. Approaches to the description of 0.1 Hz oscillations of heart rate variability and the magistral blood flowГриневичА. А.GrinevichA. A.

канд. физ.-мат. наук, старший научный сотрудник,

142290, Пущино, Московская область, ул. Институтская, д. 3

PhD, senior researcher,

142290, Moscow region, Pushchino, Institutskaya street, 3

grin_aa@mail.ruИнститут биофизики клетки Российской академии наук – обособленное подразделение Федерального государственного бюджетного учреждения науки «Федеральный исследовательский центр "Пущинский научный центр биологических исследований Российской академии наук"»; Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наукРоссияInstitute of Cell Biophysics, Russian Acad. Sci.; Institute of Theoretical and Experimental Biophysics, Russian Acad. Sci.Russian Federation2018180220191741123Copyright © Гриневич А.А., 20192019Гриневич А.А.Grinevich A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.microcirc.ru/jour/article/view/256

В обзоре сфокусировано внимание на применении методов математического моделирования в исследовании механизмов, лежащих в основе формирования низкочастотных колебаний в сердечно-сосудистой системе человека. При этом основной акцент делается на 0,1 Гц ритмы и связанные с этим авторские работы. Высказываются и обосновываются новые идеи, касающиеся принципиальной роли гидродинамических свойств сосудистого русла в формировании низкочастотных колебаний в области частоты 0,1 Гц.

The review focuses on the application of methods of mathematical modeling in the study of the mechanisms underlying the formation of low-frequency oscillations in the human cardiovascular system. The main emphasis is put on 0.1 Hz rhythms and related author’s works. New ideas about the fundamental role of the hydrodynamic properties of the vascular bed in the formation of low-frequency oscillations at the frequency of 0.1 Hz are presented and justified.

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The authors declare that there are no conflicts of interest present.