microcirculationРегионарное кровообращение и микроциркуляцияRegional blood circulation and microcirculation1682-66552712-9756Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1682-6655-2019-18-1-17-23microcirculation-289Research ArticleОБЗОРЫREVIEWSХроническая постэмболическая легочная гипертензия: возможности радионуклидных методов диагностикиChronic postembolic pulmonary embolism: the role of radionuclide imagingЗавадовскийК. В.ZavadovskyК. V.

Завадовский Константин Валерьевич – доктор медицинских наук, руководитель лаборатории радионуклидных методов исследования

634012, г. Томск, ул. Киевская, д. 111а

Zavadovsky Konstantin V. – MD, head of nuclear medicine department

634012, Tomsk, Kievskaya street, 111а

konstz@cardio-tomsk.ruГуляМ. О.GulyaМ. О.

Гуля Марина Олеговна – кандидат медицинских наук, врач-рентгенолог лаборатории радионуклидных методов исследования

634012, г. Томск, ул. Киевская, д. 111а

Gulya Marina O. – PhD, radiologist in nuclear medicine department

634012, Tomsk, Kievskaya street, 111а

gulya@cardio-tomsk.ruНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of SciencesRussian Federation2019020520191811723Copyright © Завадовский К.В., Гуля М.О., 20192019Завадовский К.В., Гуля М.О.Zavadovsky К.V., Gulya М.О.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.microcirc.ru/jour/article/view/289

Хроническая постэмболическая легочная гипертензия (ХПЛГ) является следствием хронической обструкции ветвей легочных артерий (ЛА) после однократной или повторной эмболии тромбами с последующей их организацией. Частота развития ХПЛГ у пациентов, перенесших легочную эмболию, составляет приблизительно 3,8 %. Несмотря на существенный терапевтический прогресс, ХПЛГ остается плоходиагностируемой патологией. Настоящий обзор посвящен некоторым возможностям сцинтиграфических методов в обследовании пациентов с ХПЛГ. Приведена информация о возможностях вентиляционно­пефузионной сцинтиграфии легких, равновесной радионуклидной вентрикулографии, перфузионной сцинтиграфии миокарда и сцинтиграфии сердца с 123I­МИБГ у пациентов с ХПЛГ.

Chronic postembolic pulmonary embolism (CTEPH) is the result of chronic pulmonary artery obstruction followed by pulmonary embolism. The frequency of CTEPH in patients with pulmonary embolism is approximately 3.8 %. Despite signifcant progress of pulmonary embolism management, the diagnosis of CTEPH remains diffcult. The current review is devoted to the opportunities of radionuclide methods in patients with CTEPH. The information about ventilation­perfusion scintigraphy, equilibrium radionuclide angiography, myocardial perfusion scintigraphy as well as cardiac scintigraphy with 123I­MIBG is presented.

хроническая постэмболическая легочная гипертензиявентиляционно-перфузионная сцинтиграфия легкихрадионуклидная равновесная вентрикулографияперфузионная сцинтиграфия легкихсцинтиграфия сердца с 123I-МИБГchronic postembolic pulmonary hypertensionventialtion/perfson lung scintigraphyequilibrium radionuclide angiographymyocardial perfusion scintigraphycardiac scintigraphy with 123I-MIBGReferencesPengoV, Lensing AW, Prins MH et al. Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. N Engl J Med. 2004;350:2257–2264. Doi: https://doi.org/10.1056/NEJMoa032274.PengoV, Lensing AW, Prins MH et al. Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. N Engl J Med. 2004;350:2257–2264. Doi: https://doi.org/10.1056/NEJMoa032274.Fedullo P, Kerr KM, Kim NH et al Chronic thromboembolic pulmonary hypertension. Am J RespirCrit Care Med. 2011 Jun 15;183(12):1605–1613. 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The authors declare that there are no conflicts of interest present.