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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microcirculation</journal-id><journal-title-group><journal-title xml:lang="ru">Регионарное кровообращение и микроциркуляция</journal-title><trans-title-group xml:lang="en"><trans-title>Regional blood circulation and microcirculation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-6655</issn><issn pub-type="epub">2712-9756</issn><publisher><publisher-name>Academician I.P. Pavlov First St. Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1682-6655-2015-14-4-74-79</article-id><article-id custom-type="elpub" pub-id-type="custom">microcirculation-43</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Влияние интраоперационных изменений кровотока в артерии, питающей кожно-фасциальный лоскут, на качество его приживления</article-title><trans-title-group xml:lang="en"><trans-title>The effect of intraoperative changes in the blood flow in the feeder artery of the fasciocutaneous flap on its engraftment quality (an experimental study)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щудло</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchudlo</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">nshchudlo@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щурова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchurova</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">elena.shurova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щудло</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchudlo</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">m.m.sch@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сбродова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sbrodova</surname><given-names>L. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научный центр «Восстановительная травматология и ортопедия» им. акад. Г.А. Илизарова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution "Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2015</year></pub-date><volume>14</volume><issue>4</issue><fpage>74</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Щудло Н.А., Щурова Е.Н., Щудло М.М., Сбродова Л.И., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Щудло Н.А., Щурова Е.Н., Щудло М.М., Сбродова Л.И.</copyright-holder><copyright-holder xml:lang="en">Shchudlo N.A., Shchurova E.N., Shchudlo M.M., Sbrodova L.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.microcirc.ru/jour/article/view/43">https://www.microcirc.ru/jour/article/view/43</self-uri><abstract><p>Цель. Выявление взаимосвязи интраоперационных изменений кровотока в артерии, питающей кожно-фасциальный лоскут, с качеством его приживления. Материал и методы исследования. У 16 крыс на основе поверхностной нижней эпигастральной артерии (SIEA) сформирован лоскут площадью 18 см2 и после 90-минутного периода клипирования бедренной артерии у места отхождения SIEA реплантирован. Сразу после элевации лоскута, в момент снятия клипсы с артерии и на протяжении 10 минут после снятия ультразвуковым флоуметром Т101 регистрировали объемную скорость кровотока. Через 12 дней после операции животные эвтаназированы. С помощью камеры Sony Cyber-shot DSC-HX100V в режиме макросъемки получены полноцветные цифровые изображения наружной и внутренней поверхностей лоскутов. С применением полуколичественного метода экспертных оценок определена выраженность венозной недостаточности лоскута и некроза его подкожной жировой клетчатки. Методом точко-счетной компьютерной планиметрии в цифровых изображениях наружной поверхности лоскутов определена доля дефектов эпидермиса (в процентах от площади лоскута), а при анализе изображений внутренней поверхности - доли сосудистых структур и экстравазаций. Результаты исследования. При анализе характера и величины изменения объемной скорости кровотока во время операции документированы три варианта реперфузии: гипоперфузия, умеренная гиперперфузия и выраженная транзиторная гиперперфузия. При втором варианте дефекты эпидермиса, средние оценки выраженности венозной недостаточности и некроза жировой клетчатки, а также доли экстравазаций имели наименьшие значения, а доля сосудистых структур была наибольшей. В первом варианте по сравнению со вторым достоверно выше оценка венозной недостаточности и доля экстравазаций, а в третьем варианте - оценка некроза жировой клетчатки и также доля экстравазаций. Наиболее благоприятные показатели приживления отмечены при втором варианте. Вывод. Интраоперационное исследование объемной скорости кровотока в артерии, питающей лоскут, позволяет оценить риск развития реперфузионных повреждений его сосудистого русла, венозной недостаточности и некроза подкожной жировой клетчатки.</p></abstract><trans-abstract xml:lang="en"><p>Purpose. To reveal the correlation of blood flow in the artery supplying a fasciocutaneous flap with its engraftment quality. Materials and Methods. A flap of 18 cm2 area was formed in 16 rats on the basis of the superficial inferior epigastric artery (SIEA) and replanted after 90-minute period of femoral artery clipping at the point of SIEA embranchment. The volume blood flow was registered immediately after the flap elevation, at the moment of the clip removal from the artery and for 10 minutes after the removal using T101 ultrasound flowmeter. 12 days later the animals were euthanized. True color digital images of the flap inner and outer surfaces were obtained by Sony Cyber-shot DSC-HX100V camera macro mode. Venous congestion severity of the flap and its subcutaneous fat necrosis were revealed using the semi-quantitative method of expert evaluations. The proportion of epidermis defects (in percentage of the flap area) was determined in the digital images of the flap external surface using the method of point-counting computer-assisted planimetry, and the proportion of vascular structures and extravasations was determined by analyzing the images of the inner surface. Results. Three variants of reperfusion were documented intraoperatively when analyzing the character and amount of the change in volume blood flow: hypoperfusion, moderate hyperperfusion, and severe transient hyperperfusion. In case of the second variant epidermis defects, the mean values of venous congestion severity and subcutaneous fat necrosis, as well as the proportions of extravasations were the lowest, while the percentage of vascular structures was the highest. The extent of venous congestion and the proportion of extravasations were reliably higher in the first variant in comparison with the second one. The severity of subcutaneous fat necrosis and the percentage of extravasations were higher in the third variant than in the second one. The most favorable rates of engraftment were observed for the second variant. Conclusion. The intraoperative study of volume blood flow in the artery supplying the flap allows to evaluate the risk of reperfusion injury of its vascular bed, venous congestion, and subcutaneous fat necrosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>васкуляризованный кожно-фасциальный лоскут</kwd><kwd>кровоток</kwd><kwd>флоуметрия</kwd><kwd>vascularized fasciocutaneous flap</kwd><kwd>blood flow</kwd><kwd>flow me try</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шалтакова Г. Ч., Матвеев М. А. Пластика васкуляризованными лоскутами при послеожоговых деформациях кисти // Вестник травматол. и ортопедии им. Н. Н. Приорова. 2009. № 4. С. 58-60.</mixed-citation><mixed-citation xml:lang="en">Шалтакова Г. Ч., Матвеев М. А. Пластика васкуляризованными лоскутами при послеожоговых деформациях кисти // Вестник травматол. и ортопедии им. Н. Н. Приорова. 2009. № 4. 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