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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microcirculation</journal-id><journal-title-group><journal-title xml:lang="ru">Регионарное кровообращение и микроциркуляция</journal-title><trans-title-group xml:lang="en"><trans-title>Regional blood circulation and microcirculation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-6655</issn><issn pub-type="epub">2712-9756</issn><publisher><publisher-name>Academician I.P. Pavlov First St. Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1682-6655-2019-18-3-23-28</article-id><article-id custom-type="elpub" pub-id-type="custom">microcirculation-438</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ (КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ)</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES (CLINICAL INVESTIGATIONS)</subject></subj-group></article-categories><title-group><article-title>Сопоставимость данных сцинтиграфии с результатами коронарографии после хирургической реваскуляризации миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Comparability of scintigraphy data with coronary angiography after surgical myocardial revascularization</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, зав. кабинетом рентгенохирургических методов диагностики и лечения</p></bio><bio xml:lang="en"><p>MD, PhD, head of the X-ray diagnostic and treatment methods</p></bio><email xlink:type="simple">shilaa@kemcardio.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочергин</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochergin</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, научный сотрудник лаборатории интервенционных методов диагностики и лечения</p></bio><bio xml:lang="en"><p>MD, PhD, Researcher, Laboratory of Interventional Diagnostic and Treatment Methods</p></bio><email xlink:type="simple">nikotwin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ганюков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ganyukov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, зав. лаборатории интервенционных методов диагностики и лечения</p></bio><bio xml:lang="en"><p>MD, PhD, head of the Laboratory of Interventional Diagnostic and Treatment Methods</p></bio><email xlink:type="simple">ganyukov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, зав. лабораторией рентгеновской и томографической диагностики</p></bio><bio xml:lang="en"><p>PhD, head of the Laboratory of X-ray and Tomographic Diagnostics</p></bio><email xlink:type="simple">kokoan@kemcardio.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козырин</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozyrin</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, кардиохирург отделения кардиохирургии</p></bio><bio xml:lang="en"><p>MD, PhD, Cardiac Surgeon Federal State Budgetary Scientific Institution,</p></bio><email xlink:type="simple">kozirin@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Короткевич</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotkevich</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>– врач-радиолог отделения лучевой диагностики</p></bio><bio xml:lang="en"><p>radiologist of the Department of Radiology Diagnostics</p></bio><email xlink:type="simple">koroaa@kemcardio.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>член-корреспондент РАН, директор</p></bio><bio xml:lang="en"><p>Corresponding Member RAS, director</p></bio><email xlink:type="simple">olb61@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Кемеровской области «Кемеровский областной клинический кардиологический диспансер имени академика Л. С. Барбараша»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kemerovo Regional Clinical Cardiology Clinic named after acad. L. S. Barbarasha</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Problems of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>06</day><month>10</month><year>2019</year></pub-date><volume>18</volume><issue>3</issue><fpage>23</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шилов А.А., Кочергин Н.А., Ганюков В.И., Коков А.Н., Козырин К.А., Короткевич А.А., Барбараш О.Л., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шилов А.А., Кочергин Н.А., Ганюков В.И., Коков А.Н., Козырин К.А., Короткевич А.А., Барбараш О.Л.</copyright-holder><copyright-holder xml:lang="en">Shilov A.A., Kochergin N.A., Ganyukov V.I., Kokov A.N., Kozyrin K.A., Korotkevich A.A., Barbarash O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.microcirc.ru/jour/article/view/438">https://www.microcirc.ru/jour/article/view/438</self-uri><abstract><sec><title>Введение</title><p>Введение. Радионуклидная визуализация включена в методы диагностики после чрескожного коронарного вмешательства (ЧКВ) и аортокоронарного шунтирования (АКШ) у пациентов с симптомами, но рекомендации предостерегают от ее рутинного тестирования у всех бессимптомных пациентов после реваскуляризации. В работе показаны результаты однофотонной эмиссионной компьютерной томографии (ОФЭКТ) после гибридной коронарной реваскуляризации миокарда, проведен анализ чувствительности и специфичности трех методов хирургической реваскуляризации миокарда через 12 месяцев.</p><p>Цель исследования – определение чувствительности и специфичности ОФЭКТ в определении стенозов коронарных артерий ≥50 % после выполнения трех методов хирургической реваскуляризации миокарда – АКШ, ЧКВ и гибридной реваскуляризации миокарда у больных с ишемической болезнью сердца (ИБС) и многососудистым поражением коронарного русла.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведен ретроспективный анализ 82 пациентов со стабильными формами ИБС, которым была проведена реваскуляризация миокарда по поводу наличия многососудистого поражения коронарного русла. Пациенты разделены на 3 группы: 1-ю группу составили 40 больных, которым выполнили процедуру АКШ, 2-ю ‒ 29 пациентов после ЧКВ и 3-ю ‒ 23 больных, которым проведена гибридная реваскуляризация миокарда.</p></sec><sec><title>Результаты</title><p>Результаты. Все пациенты после реваскуляризации миокарда в среднем через 21,8±8,6 месяца госпитализировались в стационар, где проводилась ОФЭКТ миокарда с 99mTc-технетрилом и контрольная коронарография/шунтография. Частота наличия значимого стеноза при коронарографии при дефекте перфузии ≥5 % на ОФЭКТ во время нагрузки составила в группах АКШ, ЧКВ и гибридной реваскуляризации соответственно 50, 50 и 33 % (p=0,894). Наименьшая чувствительность ОФЭКТ была после гибридной реваскуляризации миокарда (20 %), в то время как в группе АКШ чувствительность составила 71,4 % (p=0,190). Показатели специфичности ОФЭКТ были гораздо выше: в группах АКШ, ЧКВ и гибридной реваскуляризации, соответственно 75,8, 79 и 88,9 % (p=0,530).</p></sec><sec><title>Выводы</title><p>Выводы. У пациентов после проведенной реваскуляризации миокарда отсутствует достоверная взаимосвязь между размерами дефекта на ОФЭКТ и данными коронарографии вне зависимости от вида хирургической реваскуляризации миокарда. Выявление дефекта перфузии при нагрузке более 10 % при ОФЭКТ после проведенной хирургической реваскуляризации миокарда является основанием для проведения коронарографии с целью исключения рестеноза стента или дисфункции шунта, а также прогрессирования коронарного атеросклероза.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Radionuclide imaging is included in diagnostic methods after PCI and CABG in patients with symptoms, but the recommendations caution against routine testing in all asymptomatic patients after revascularization. The paper shows the results of single-photon emission computed tomography after hybrid coronary myocardial revascularization; an analysis of the sensitivity and specificity of three methods of surgical myocardial revascularization was carried out in 12 months.</p><p>Aim of the study was to determine the sensitivity and specificity of SPECT in determining coronary artery stenosis ≥ 50 % after performing three methods of surgical myocardial revascularization: CABG, PCI, and hybrid myocardial revascularization in patients with coronary artery disease and multi-vascular coronary lesion.</p></sec><sec><title>Material and methods</title><p>Material and methods. A retrospective analysis of 82 patients with stable forms of coronary artery disease who underwent myocardial revascularization for the presence of the multivascular coronary lesion was carried out. The patients were divided into three groups: the first group consisted of 40 patients who underwent CABG, the second – 29 patients after PCI, and the third – 23 patients who underwent hybrid myocardial revascularization.</p></sec><sec><title>Results</title><p>Results. All patients after myocardial revascularization, on average, after 21.8±8.6 months, were hospitalized, where singlephoton emission computed tomography of the myocardium with 99mTc-technetril (SPECT) and control coronarography/ shuntography were performed. The frequency of the presence of significant stenosis during coronary angiography with a perfusion defect of ≥5 % on SPECT during exercise was 50, 50 and 33 % in the CABG, PCI, and hybrid revascularization, respectively (p=0.894). The least sensitivity of SPECT was after hybrid myocardial revascularization (20 %), while in the CABG group, the sensitivity was 71.4 % (p = 0.190). The SPECT specificity indices were much higher: in the GABG, PCI, and hybrid revascularization groups, respectively, 75.8, 79 and 88.9 % (p=0.530).</p></sec><sec><title>Conclusion</title><p>Conclusion. There is no significant relationship between the size of the defect on SPECT and coronary angiography data, regardless of the type of surgical myocardial revascularization in patients after myocardial revascularization. Detection of a perfusion defect with a load of more than 10% in SPECT after surgical myocardial revascularization is the basis for coronary angiography in order to exclude stent restenosis or shunt dysfunction, as well as progression of coronary atherosclerosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гибридная коронарная реваскуляризация</kwd><kwd>аортокоронарное шунтирование</kwd><kwd>MIDCAB</kwd><kwd>чрескожное коронарное вмешательство</kwd><kwd>сцинтиграфия миокарда</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hybrid coronary revascularization</kwd><kwd>CABG</kwd><kwd>MIDCAB</kwd><kwd>PCI</kwd><kwd>myocardial scintigraphy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Остроумов Е. Н. Где нужна ядерная кардиология? // Рос. кардиолог. журн. – 2009. – № 5 (79). – С. 4–9. 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