microcirculationРегионарное кровообращение и микроциркуляцияRegional blood circulation and microcirculation1682-66552712-9756Academician I.P. Pavlov First St. Petersburg State Medical University10.24884/1682-6655-2012-11-2-4-10microcirculation-457Research ArticleСтатьиКальциноз аорты и магистральных артерий: патобиологические механизмы и клиническая значимость.Aorta and major arteries calcinosis: pathobiological mechanisms and clinical significanceМельниковМ. В.MelnikovM. V.noemail@neicon.ruБарсуковА. Е.BarsukovA. E.noemail@neicon.ruЗелинскийВ. А.ZelinskiyV. A.zelinsky2@rambler.ruАпресянА. Ю.ApresyanA. U.noemail@neicon.ruСеверо-Западный государственный медицинский университет имени И. И. МечниковаРоссияGeneral surgery department of the Northwest state medical university named after I. I. MechnikovRussian Federation201230062012112410Copyright © Мельников М.В., Барсуков А.Е., Зелинский В.А., Апресян А.Ю., 20122012Мельников М.В., Барсуков А.Е., Зелинский В.А., Апресян А.Ю.Melnikov M.V., Barsukov A.E., Zelinskiy V.A., Apresyan A.U.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.microcirc.ru/jour/article/view/457

Представленный литературный обзор, посвящен проблеме кальцификации стенки аорты и магистральных артерий. Дана подробная сравнительная характеристика отдельных видов кальциноза. Основное внимание уделено двум наиболее часто встречающимся видам кальцификации артериальной стенки: интимальному кальцинозу и медиакальцинозу (склерозу Менкеберга). На основании анализа доступной литературы описаны возможные причины и патогенетические механизмы развития данных патологических состояний. Большое внимание уделено клиническому значению кальцификации стенки брюшной аорты. Проанализирована связь между кальцинозом брюшной аорты и риском развития сердечно-сосудистых осложнений.

The present review is devoted to the problem of the aorta and major arteries wall calcification. In this paper the comparative description of different types of calcinosis is presented. The main notice of article is focused on the intimal- and mediacalcinosis (Monckeberg's sclerosis) as a kinds with a more common incidence in general population. Through the literatures data, possibly causes and pathogenetic mechanisms of calcinosis are described. The great attention is given to a clinical value of an abdominal aorta wall calcinosis. In conclusion, the relationship between abdominal aortic calcification and high risk of cardiovascular events is analyzed.

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The authors declare that there are no conflicts of interest present.