References

microcirculation

Регионарное кровообращение и микроциркуляция

Regional blood circulation and microcirculation

1682-66552712-9756

Academician I.P. Pavlov First St. Petersburg State Medical University

10.24884/1682-6655-2012-11-4-12-17

microcirculation-827

Research Article

ОБЗОРЫ

REVIEWS

Предикторы и сывороточные маркеры кальциноза брюшной аорты

Predictors and blood markers of abdominal aortic calcification

Мельников

М. В.

Melnikov

M. V.

noemail@neicon.ru

Зелинский

В. А.

Zelinskiy

V. A.

zelinsky2@rambler.ru

Апресян

А. Ю.

Apresyan

A. U.

noemail@neicon.ru

Северо-Западный государственный медицинский университет им. И. И. МечниковаРоссияNorth-Western state medical university named after I. I. MechnikovRussian Federation

2012

30122012

1141217

2012

Мельников М.В., Зелинский В.А., Апресян А.Ю.

Melnikov M.V., Zelinskiy V.A., Apresyan A.U.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.microcirc.ru/jour/article/view/827

Кальциноз брюшной аорты, по мнению целого ряда исследователей, одновременно является предиктором генерализованного атеросклероза и существенно осложняет его течение. В представленном литературном обзоре анализируется роль различных факторов риска, маркеров кальциноза брюшной аорты. Следует считать доказанным значение табакокурения, артериальной гипертензии и сахарного диабета в развитии кальциноза брюшной аорты. В то же самое время роль сывороточных маркеров (липиды, остеопротегерин, остеопонтин, С-реактивный белок, гомоцистеин, фетуин-А) в процессе развития кальцификации аорты остается дискутабельной и требует дальнейшего изучения.

Some authors are reported that abdominal aortic calcification is a strong predictor of systematic atherosclerosis and significantly impacts to the atherosclerotic burden. This review summarizes the present knowledge regarding risk factors and markers of abdominal aortic calcification. Well established risk factors for abdominal aortic calcification included smoking, arterial hypertension and diabetes mellitus. The role of blood markers (such as lipids, osteoprotegerin, osteopontin, C-reactive protein, homocysteine, fetuin-A) as risk factors for abdominal aortic calcification is debated. Further studies are required to critically assess the role of outlines blood markers.

кальциноз брюшной аортымаркерпредикторфактор рискаabdominal aortic calcificationmarkerpredictorrisk factor

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The authors declare that there are no conflicts of interest present.