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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microcirculation</journal-id><journal-title-group><journal-title xml:lang="ru">Регионарное кровообращение и микроциркуляция</journal-title><trans-title-group xml:lang="en"><trans-title>Regional blood circulation and microcirculation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-6655</issn><issn pub-type="epub">2712-9756</issn><publisher><publisher-name>Academician I.P. Pavlov First St. Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1682-6655-2020-19-4-53-60</article-id><article-id custom-type="elpub" pub-id-type="custom">microcirculation-879</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ (КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ)</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES (CLINICAL INVESTIGATIONS)</subject></subj-group></article-categories><title-group><article-title>Сравнительная оценка инструментальных методик исследования состояния эндотелия при сахарном диабете II типа</article-title><trans-title-group xml:lang="en"><trans-title>Comparative evaluation of instrumental methods for studying the state of endothelium in type II diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малахова</surname><given-names>З. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Malakhova</surname><given-names>Z. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малахова Зинаида Леонидовна – врач ультразвуковой диагностики отделения</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>Malakhova Zinaida L. – MD, Department of Ultrasound Diagnostics</p><p>6-8, L’va Tolstogo str., Saint Petersburg, 197022</p></bio><email xlink:type="simple">zinaida.malahova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симаненкова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Simanenkova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симаненкова Анна Владимировна – канд. мед. наук, ассистент кафедры терапии факультетской с курсом эндокринологии, кардиологии и функциональной диагностики с клиникой</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>Simanenkova Anna V. – MD, PhD, assistant of faculty therapy department</p><p>6-8, L’va Tolstogo str., Saint Petersburg, 197022</p></bio><email xlink:type="simple">annasimanenkova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митрейкин</surname><given-names>В. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitreikin</surname><given-names>V. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Митрейкин Владимир Филиппович – д-р мед. наук, профессор кафедры патофизиологии с курсом клинической патофизиологии</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>Mitreikin Vladimir F. – MD, PhD, Dr. of Sci. (Med.), Professor, Department of Pathophysiology</p><p>6-8, L’va Tolstogo str., Saint Petersburg, 197022</p></bio><email xlink:type="simple">mvphch2742@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амосов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Amosov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Амосов Виктор Иванович – д-р мед. наук, профессор, зав. кафедрой рентгенологии и радиационной медицины с рентгенологическим и радиологическим отделениями</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>Amosov Viktor I. – Dr. of Sci. (Med.), professor, head of the Department of Radiology and Radiation Medicine</p><p>6-8, L’va Tolstogo str., Saint Petersburg, 197022</p></bio><email xlink:type="simple">vikt-amosov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власов</surname><given-names>Т. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasov</surname><given-names>T. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Власов Тимур Дмитриевич – д-р мед. наук, профессор, зав. кафедрой патофизиологии с курсом клинической патофизиологии</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>Vlasov Timur D. – Dr. of Sci. (Med.), professor, head of the Department of Pathophysiology with a course of clinical pathophysiology</p><p>6-8, L’va Tolstogo str., Saint Petersburg, 197022</p></bio><email xlink:type="simple">tvlasov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>24</day><month>12</month><year>2020</year></pub-date><volume>19</volume><issue>4</issue><fpage>53</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малахова З.Л., Симаненкова А.В., Митрейкин В.Ф., Амосов В.И., Власов Т.Д., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Малахова З.Л., Симаненкова А.В., Митрейкин В.Ф., Амосов В.И., Власов Т.Д.</copyright-holder><copyright-holder xml:lang="en">Malakhova Z.L., Simanenkova A.V., Mitreikin V.F., Amosov V.I., Vlasov T.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.microcirc.ru/jour/article/view/879">https://www.microcirc.ru/jour/article/view/879</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>эндотелий</kwd><kwd>потокозависимая вазодилатация</kwd><kwd>ацетилхолинзависимая вазодилатация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endothelium</kwd><kwd>flow-dependent vasodilation</kwd><kwd>acetylcholine-dependent vasodilation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Flammer AJ, Lüscher TF. 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