The purpose of work is to conduct a mathematical analysis of the relationship of central hemodynamic parameters (CHP) with blood flow indicators in the microvascular bed (MVB) in the skin of people and linear and volume indicators of blood flow in the MVB. Materials and methods. The analysis of CHP parameters (HR, BPs, BPd, BPp) with linear and volumetric parameters of blood flow in the MVB in 25 healthy men (19–60 years old), at rest, during the stress test in the bicycle ergometry, in the recovery period (RP) was performed. The parameters of blood flow in the MVB were measured by high-frequency ultrasound dopplerography on the skin of the finger nail fold with 20 MHz sensor. For analysis one-factor dispersion analysis (ANOVA) with Fisher criterion (p≤0.05), the method of main components, the Shapiro–Wilk criterion, LSD-criterion and the Tukey criterion were used. Results. There is a relationship between indicators of the CHP (HR, BPs, BPd, BPp) and parameters of blood flow in the MVB: maximum systolic velocity (Vs), maximum average velocity (Vm), maximum diastolic velocity (Vd) in the MVB during the stress test in the bicycle ergometry and in the RP. The indicators were divided in 3 groups after converting in the new coordinate system. Group 1 (n=10) was characterized by good blood flow of the capillary part of MVB (Vam=0.41±0.14 сm/s). Group 2 (n=8) had a reduced blood flow (Vam =0.16±0.06 сm/s). In group 3 (n=7), the capillary blood flow indices were low (Vam=0.115±0.07сm/s), but there was a high blood flow velocity in the arteriolar part (Vs=1.89±0.3 сm/s). Conclusions. The mathematical analysis showed the relationship of blood flow parameters in the arteriolar part of the MVB with indicators of the CHP. Indicators of blood flow in the arteriolar and capillary parts of the MVB in the skin of healthy people at rest differ in velocity and blood filling.