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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microcirculation</journal-id><journal-title-group><journal-title xml:lang="ru">Регионарное кровообращение и микроциркуляция</journal-title><trans-title-group xml:lang="en"><trans-title>Regional blood circulation and microcirculation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-6655</issn><issn pub-type="epub">2712-9756</issn><publisher><publisher-name>Academician I.P. Pavlov First St. Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1682-6655-2021-20-1-84-90</article-id><article-id custom-type="elpub" pub-id-type="custom">microcirculation-930</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ (ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ)</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES (EXPERIMENTAL INVESTIGATIONS)</subject></subj-group></article-categories><title-group><article-title>Структура взаимосвязей показателей аэробной работоспособности, центральной гемодинамики, микроциркуляции и реологии крови</article-title><trans-title-group xml:lang="en"><trans-title>The structure of the relationship between indicators of aerobic performance, central hemodynamics, microcirculation and hemorheology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1491-3882</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhaylov</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михайлов Павел Валентинович – кандидат биологических наук, доцент кафедры спортивных дисциплин</p><p>150000, г. Ярославль, ул. Республиканская, д. 108/1 </p></bio><bio xml:lang="en"><p>Mikhaylov Pavel V. – Cand. of Sci. (Biol.), associate professor of the department of sports disciplines</p><p>108/1, Respublikanskaya str., Yaroslavl, 150000</p></bio><email xlink:type="simple">mpv.yar@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5502-9164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravyov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муравьев Алексей Васильевич – доктор биологических наук, профессор кафедры медико-биологических основ спорта</p><p>150000, г. Ярославль, ул. Республиканская, д. 108/1 </p></bio><bio xml:lang="en"><p>Muravyov Alexey V. – Doctor of biological sciences, professor of the department of medical and biological foundations of sports</p><p>108/1, Respublikanskaya str., Yaroslavl, 150000</p></bio><email xlink:type="simple">alexei.47@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3269-2262</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осетров</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Osetrov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Осетров Игорь Александрович – кандидат биологических наук, доцент кафедры спортивных дисциплин</p><p>150000, г. Ярославль, ул. Республиканская, д. 108/1 </p></bio><bio xml:lang="en"><p>Osetrov Igor A. – Cand. of Sci. (Biol.), associate professor of the department of sports disciplines</p><p>108/1, Respublikanskaya str., Yaroslavl, 150000</p></bio><email xlink:type="simple">igos@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроумов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostroumov</surname><given-names>R S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Остроумов Роман Сергеевич – преподаватель кафедры физической подготовки</p><p>150000, г. Ярославль, ул. Республиканская, д. 108/1 </p></bio><bio xml:lang="en"><p>Ostroumov Roman S. – teacher of the department of physical training, Yaroslavl higher military school of air defense</p><p>108/1, Respublikanskaya str., Yaroslavl, 150000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9521-4017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихомирова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikhomirova</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тихомирова Ирина Александровна – доктор биологических наук, профессор, заведующая кафедрой медицины, биологии, теории и методики обучения биологии</p><p>150000, г. Ярославль, ул. Республиканская, д. 108/1 </p></bio><bio xml:lang="en"><p>Tikhomirova Irina A. – Doctor of biological sciences, professor, head of department of medicine, biology, theory and methods of teaching biology</p><p>108/1, Respublikanskaya str., Yaroslavl, 150000</p></bio><email xlink:type="simple">tikhom-irina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Ярославский государственный педагогический университет имени К. Д. Ушинского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yaroslavl State Pedagogical University named after K. D. Ushinsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>21</day><month>03</month><year>2021</year></pub-date><volume>20</volume><issue>1</issue><fpage>84</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайлов П.В., Муравьев А.В., Осетров И.А., Остроумов Р.С., Тихомирова И.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Михайлов П.В., Муравьев А.В., Осетров И.А., Остроумов Р.С., Тихомирова И.А.</copyright-holder><copyright-holder xml:lang="en">Mikhaylov P.V., Muravyov A.V., Osetrov I.A., Ostroumov R.S., Tikhomirova I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.microcirc.ru/jour/article/view/930">https://www.microcirc.ru/jour/article/view/930</self-uri><abstract><sec><title>Введение</title><p>Введение. Поиск взаимосвязей между параметрами, характеризующими функциональное состояние организма на разных его уровнях, является важной задачей при проведении исследований в области физиологии. Поскольку эти взаимосвязи могут быть сложными, опосредованными дополнительными факторами и при использовании парной корреляции не выявляться, то в этом случае представляется оправданным для поиска скрытой структуры связей множества переменных применение факторного анализа.</p><p>Цель – проведение факторного анализа комплекса данных, включающего показатели аэробной работоспособности, центральной гемодинамики, микроциркуляции (МЦ) и реологии крови.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследовании приняли участие 172 мужчины в возрасте от 20 до 60 лет. Уровень физической работоспособности оценивали по результатам теста PWC170. Параметры МЦ определяли с помощью метода биомикроскопии и лазерной допплеровской визуализации (LDI). Среди гемореологических характеристик измеряли вязкость крови и плазмы, агрегацию и деформируемость эритроцитов. Статистическую обработку полученных данных, включающую факторный анализ, проводили с использованием программного пакета «Statistica 6.0». При построении факторной модели, включающей 32 параметра, учитывались переменные с факторной нагрузкой более 0,60.</p></sec><sec><title>Результаты</title><p>Результаты. Было выделено три фактора, которые составили 71 % от общей дисперсии. Первый фактор был тесно взаимосвязан с параметрами, характеризующими уровень аэробной производительности организма и его адаптационный потенциал. Второй фактор коррелировал с параметрами системы кровообращения, характеризующими условия гемодинамики на центральном уровне и микроциркуляторном, включая интегральные реологические показатели. Третий фактор был взаимосвязан с параметрами, характеризующими кровоток на уровне микрососудов, а также реологические свойства эритроцитов.</p></sec><sec><title>Заключение</title><p>Заключение. Построенная факторная модель демонстрирует иерархическую структуру взаимосвязей показателей аэробной работоспособности, центральной гемодинамики, МЦ, реологии крови. Выделенные факторы – скрытые элементы этой структуры, связывающие отдельные переменные, – были интерпретированы как уровни интеграции: организменный, системный и микроуровневый.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. In physiological research, an important task is to find the relationship between the various functional parameters of the organism, its individual systems and its elements. These relationships can be complex, mediated by additional factors and when using pair correlation, they cannot be detected. In this case, it seems justified to use factor analysis to search for the hidden structure of relationships between many variables. The aim. Factor analysis of a set of data, including indicators of aerobic performance, central hemodynamics, microcirculation (MC) and hemorheology.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study involved 172 men aged 20 to 60 years. Physical performance was determined using the PWC170 test. Microcirculation parameters were determined using biomicroscopy and Laser Doppler Imaging (LDI). The complex of hemorheological characteristics included the viscosity of blood and plasma, aggregation and deformability of erythrocytes. Statistical processing, including factor analysis, was carried out using the Statistica 6.0 software package. The factorial model included 32 parameters. When interpreting the results of factor analysis, variables with factor loadings of more than 0.60 were considered.</p></sec><sec><title>Results</title><p>Results. Three factors were identified, which accounted for 71 % of the total variance. The first factor closely correlated with the level of the body’s aerobic performance parameters and its adaptive potential. The second factor correlated with hemodynamic parameters at the central and microcirculatory level, including integral rheological parameters. The third factor correlated with the parameters of microvessels and the rheological properties of erythrocytes.</p></sec><sec><title>Conclusions</title><p>Conclusions. The constructed factor model demonstrates the level structure of the relationships of indicators of aerobic performance, central hemodynamics, microcirculation, and hemorheology. The selected factors – the hidden elements of this structure linking individual variables – were interpreted as levels of integration: organismic, systemic and microlevel.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>факторный анализ</kwd><kwd>аэробная работоспособность</kwd><kwd>микроциркуляция</kwd><kwd>реологические свойства крови</kwd><kwd>деформируемость эритроцитов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>factor analysis</kwd><kwd>aerobic performance</kwd><kwd>microcirculation</kwd><kwd>rheological properties of blood</kwd><kwd>deformability of erythrocytes</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке РФФИ и БРФФИ в рамках научного проекта № 20-515-00019</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pries AR, Secomb TW. Rheology of the microcirculation. Clin. 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