The experience of clinical trials radiopharmaceutical «Yodofen» in the complex assessment of myocardium in the surgical treatment of patients with valvular heart disease
https://doi.org/10.24884/1682-6655-2012-11-3-51-56
Abstract
The article contains results approbation radiopharmaceutical «Yodofen» that is used to complex evaluation of myocardium in patients with valvular heart disease before and after surgery. The study involved 10 patients, 8 of them after surgical treatment of valvular heart disease. The study included perfusion and metabolic (capture fatty acids) gated single-photon emission computed tomography (SPECT) with radiopharmaceuticals «Tehnetril» and «Yodofen» respectively. In patients with valvular heart disease in the functional state of rest has been a violation of perfusion, metabolism of fatty acids and regional left ventricular contractility, which may persist after surgical correction of valvular heart disease. SPECT with the RP «Yodofen» can be used in patients with valvular heart disease in order to assess the state of myocardial metabolism before and after surgical treatment.
About the Authors
N. V. Mayorov
Saint-Petersburg State Medical University n. a. I. P. Pavlov
Russian Federation
Russian Federation
V. V. Davydenko
Saint-Petersburg State Medical University n. a. I. P. Pavlov
Russian Federation
Russian Federation
V. I. Amosov
Saint-Petersburg State Medical University n. a. I. P. Pavlov
Russian Federation
Russian Federation
S. V. Lapekin
Saint-Petersburg State Medical University n. a. I. P. Pavlov
Russian Federation
Russian Federation
A. A. Pushkarev
Saint-Petersburg State Medical University n. a. I. P. Pavlov
Russian Federation
Russian Federation
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Review
For citations:
Mayorov N.V., Davydenko V.V., Amosov V.I., Lapekin S.V., Pushkarev A.A. The experience of clinical trials radiopharmaceutical «Yodofen» in the complex assessment of myocardium in the surgical treatment of patients with valvular heart disease. Regional blood circulation and microcirculation. 2012;11(3):51-56. (In Russ.) https://doi.org/10.24884/1682-6655-2012-11-3-51-56
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