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Activated histamine and serotonin, intracellular and extracellular sources of calcium for the stimulation of contractile activity of lymphatic vessels of white rats

https://doi.org/10.24884/1682-6655-2012-11-3-64-68

Abstract

Histamine and serotonin stimulate the rate of lymphatic vessel pumping by the increasing cytosolic Ca2+ concentration. Histamine increases the movement of Ca2+ through plasma membrane ligand or voltage gated Ca2+ channels and thorough release of Ca2+ from internal IP3-sensitive stores. Serotonin in low concentrations increases the movement of Ca2+ through plasma membrane ligand or voltage gated Ca2+ channels and the movement of Ca2+ from internal IP3-sensitive stores and in higher concentrations use also ryanodine sensitive stores.

About the Authors

A. A. Egorova
The Sechenov Institute of Evolutionary Physiology and Biochemistry
Russian Federation


S. G. Petunov
The Sechenov Institute of Evolutionary Physiology and Biochemistry
Russian Federation


E. A. Avramenko
The Sechenov Institute of Evolutionary Physiology and Biochemistry
Russian Federation


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Review

For citations:


Egorova A.A., Petunov S.G., Avramenko E.A. Activated histamine and serotonin, intracellular and extracellular sources of calcium for the stimulation of contractile activity of lymphatic vessels of white rats. Regional blood circulation and microcirculation. 2012;11(3):64-68. (In Russ.) https://doi.org/10.24884/1682-6655-2012-11-3-64-68

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