Inflammation and cognitive function in patients with metabolic syndrome
https://doi.org/10.24884/1682-6655-2017-16-1-38-42
Abstract
The purpose of this study was to explore the relationship between the level of C-reactive protein and fibrinogen, and indices of cognitive function in patients with metabolic syndrome. As a result of this study, it was demonstrated that patients with metabolic syndrome and cognitive impairment compared with the group without cognitive disorders was higher parameters of inflammation. The increase in C-reactive protein was associated with reduced memory and increased speed of reaction and ability to concentrate, whereas an increase in fibrinogen levels was associated with lower indicators of the processes of storing, preserving and reproduction of information, logical memory and orientation in time and space. Activation of inflammation could reflect one of the possible pathophysiological mechanisms that affect the development of cognitive deficits in patients with metabolic syndrome.
About the Authors
I. B. Zueva
Federal North-West medical research centre named after V. A. Almazov; Saint-Petersburg medical-social Institute
Russian Federation
Russian Federation
D. S. Krivonosov
Federal North-West medical research centre named after V. A. Almazov; Saint-Petersburg medical-social Institute
Russian Federation
Russian Federation
E. L. Urumova
Federal North-West medical research centre named after V. A. Almazov
Russian Federation
Russian Federation
A. V. Butch
Federal North-West medical research centre named after V. A. Almazov
Russian Federation
Russian Federation
A. Y. Smirnova
Federal North-West medical research centre named after V. A. Almazov
Russian Federation
Russian Federation
E. R. Baranzevich
Federal North-West medical research centre named after V. A. Almazov; Pavlov First Saint Petersburg State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Zueva I.B., Krivonosov D.S., Urumova E.L., Butch A.V., Smirnova A.Y., Baranzevich E.R. Inflammation and cognitive function in patients with metabolic syndrome. Regional blood circulation and microcirculation. 2017;16(1):38-42. (In Russ.) https://doi.org/10.24884/1682-6655-2017-16-1-38-42
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