Modern Concepts of Maintaining Functional Capacity of Autologous Radial Artery Vascular Grafts Used in Coronary Artery Bypass Grafting (review)
https://doi.org/10.24884/1682-6655-2026-25-1-4-14
Abstract
This review summarizes studies on radial artery autograft vasospasms in coronary artery bypass grafting, and analyzes possible causes of grafted artery vasospasm. Coronary artery bypass grafting has proven the most effective method for correcting the consequences of coronary heart disease. Spasmophilia of arterial bypass grafts in the intraand postoperative period is currently amenable to pharmacological control. Arterial spasms are mediated by the tonic activity of smooth muscle cells in the vessel media in response to many different factors. The exact mechanisms of spasms and the reasons for their development remain unclear; however, clinical practice requires assessment of the functional bypass graft viability. The review analyzes possible causes of radial artery conduit vasospasms and existing methods for controlling the tone of arterial bypass grafts. Research in this area may expand the indications for the use of arterial bypass grafts and predict their long-term functional viability.
About the Authors
E. A. Golovanov
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Golovanov Egor A. – Junior researcher, Research Institute of Cardiology.
111-A, Kiyevskaya str., Tomsk, 634012
S. A. Afanasyev
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Afanasyev Sergey A. – Dr. of Sci. (Med.), Professor; Head, Laboratory of Molecular Cell Pathology and Gene Diagnostics, Research Institute of Cardiology.
111-A, Kiyevskaya str., Tomsk, 634012
V. V. Zatolokin
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Zatolokin Vasily V. – Candidate (PhD) of Medical Sciences, Researcher, Research Institute of Cardiology.
111-A, Kiyevskaya str., Tomsk, 634012
D. S. Kondratieva
Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Kondratieva Dina S. – Dr. of Sci. (Med.), Senior Researcher, Research Institute of Cardiology.
111-A, Kiyevskaya str., Tomsk, 634012
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Review
For citations:
Golovanov E.A., Afanasyev S.A., Zatolokin V.V., Kondratieva D.S. Modern Concepts of Maintaining Functional Capacity of Autologous Radial Artery Vascular Grafts Used in Coronary Artery Bypass Grafting (review). Regional blood circulation and microcirculation. 2026;25(1):4-14. (In Russ.) https://doi.org/10.24884/1682-6655-2026-25-1-4-14
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