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Arterial stiffness in correlation with cardiovascular risk factors in hypertensive patients (population study)

https://doi.org/10.24884/1682-6655-2014-13-3-17-22

Abstract

Purpose. To study the parameters of local stiffness of arterial wall in correlation with cardiovascular risk factors in hypertensive patients. Material and methods. We carried out cross-sectional population study of workers of an industrial enterprise. The study included 213 individuals, among which 106 had arterial hypertension stage I-II and 107 were healthy. We made the assessment of the stage and grade of hypertension, additional categories of cardiovascular risk, as well as that of behavioral and biological risk factors in accordance with national guidelines. All the patients underwent ultrasound examination of the carotid arteries with simultaneous evaluation of arterial stiffness. Results. With the progression of hypertension there is a trend to increased vascular stiffness. Indicators of vascular stiffness were associated not only with age and level of blood pressure, but also with the anthropometric parameters and the level of apolipoprotein A and ratio Apo B/Apo A. Conclusion. Age, abdominal obesity, altered metabolism of apolipoproteins, and history of hypertension may predict increased arterial stiffness.

About the Authors

O. Yu. Bastrikov
South Ural State Medical University
Russian Federation


E. A. Grigoricheva
South Ural State Medical University
Russian Federation


V. V. Belov
South Ural State Medical University
Russian Federation


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Review

For citations:


Bastrikov O.Yu., Grigoricheva E.A., Belov V.V. Arterial stiffness in correlation with cardiovascular risk factors in hypertensive patients (population study). Regional blood circulation and microcirculation. 2014;13(3):17-22. (In Russ.) https://doi.org/10.24884/1682-6655-2014-13-3-17-22

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ISSN 1682-6655 (Print)
ISSN 2712-9756 (Online)