Free radicals metabolism in activation intravascular coagulation and fibrinolysis and mitochondrial disfunction
https://doi.org/10.24884/1682-6655-2012-11-2-43-46
Abstract
We studied thiobarbituric acid reactive substances (TBARS), superoxide dismutase activity (SOD) and SH-group level in plasma of 38 patients with activation of intravascular coagulation and fibrinolysis (AIVCF). The D-dimer level in plasma was > 500 mkg/l. It was found the elevated concentration TBARS and decrease SOD activity and SH-group level in plasma of patients with lactoacidemia. The increased SOD activity and D-dimer level negatively correlated in AIVCF.
About the Authors
L. A. Alexandrova
SC Department of Biochemistry, The Saint Petersburg State Pavlov Medical University; V. A. Almasov Federal Heart, Blood and Endocrinology Center
Russian Federation
Russian Federation
A. A. Zhloba
SC Department of Biochemistry, The Saint Petersburg State Pavlov Medical University; V. A. Almasov Federal Heart, Blood and Endocrinology Center
Russian Federation
Russian Federation
T. F. Subbotina
SC Department of Biochemistry, The Saint Petersburg State Pavlov Medical University; V. A. Almasov Federal Heart, Blood and Endocrinology Center
Russian Federation
Russian Federation
E. G. Mayewskaya
SC Department of Biochemistry, The Saint Petersburg State Pavlov Medical University
Russian Federation
Russian Federation
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Review
For citations:
Alexandrova L.A., Zhloba A.A., Subbotina T.F., Mayewskaya E.G. Free radicals metabolism in activation intravascular coagulation and fibrinolysis and mitochondrial disfunction. Regional blood circulation and microcirculation. 2012;11(2):43-46. (In Russ.) https://doi.org/10.24884/1682-6655-2012-11-2-43-46
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