Preview

Regional blood circulation and microcirculation

Advanced search

Noninvasive assessment of coronary blood flow parameters during an exercise test in patients with arterial hypertension

https://doi.org/10.24884/1682-6655-2016-15-1-50-55

Abstract

Purpose. The aim of our study was to non-invasively investigate the parameters of coronary blood flow during exercise in patients with arterial hypertension. Materials and Methods. We enrolled 144 patients with arterial hypertension. All patients performed supine bicycle symptoms-limited tests. Throughout the exercise, the diastolic peaks of coronary flow velocity in left anterior descending artery (LAD) were measured. The values of diastolic velocity before and at maximal exercise, coronary flow velocity reserve (CFVR) and difference between peak and rest velocities were calculated offline. The control group consisted of 145 healthy persons. Results. The rest blood flow velocity in LAD was 33.0±8.4 cm/s, the peak velocity in LAD was 80.3±16.5 cm/s, difference of velocities was 48.2±13.9 cm/s, CFVR was 2.55±0.56. Women and men were comparable in velocity parameters during exercise test. There was no significant correlation between mass/index of left ventricle mass and velocity data in LAD. Hypertensive patients were comparable in investigated coronary artery flow parameters with healthy group. Conclusions. During supine bicycle tests, the patients with arterial hypertension have a similar coronary artery flow velocity profile with healthy persons.

About the Authors

A. V. Zagatina
Cardiology center «Medika»
Russian Federation


N. T. Zhuravskaya
Cardiology center «Medika»
Russian Federation


Y. P. Vareldzhyan
Cardiology center «Medika»
Russian Federation


References

1. Бощенко А. А., Врублевский А. В. Коронарный резерв в диагностике гемодинамически значимых стенозов магистральных коронарных артерий: трансторакальное ультразвуковое исследование // Патология кровообращения и кардиохирургия. 2010. № 4. C. 104-106.

2. Загатина А. В., Журавская Н. Т., Крылова Л. Г. Неинвазивная оценка кровотока в левой коронарной артерии во время физической нагрузки. Трехлетний прогноз // Мед. визуализация. 2015. № 2. C. 45-53.

3. Antony I., Nitenberg A., Foult J. M., Aptecar E. Coronary vasodilator reserve in untreated and treated hypertensive patients with and without left ventricular hypertrophy // Journal of Am. College of Cardiology. 1993. Vol. 22. №2. P. 514-520.

4. Galderisi M., de Simone G., Cicala S. et al. Coronary flow reserve in hypertensive patients with appropriate or inappropriate left ventricular mass // J. of Hypertension. 2003. Vol. 21. № 11. P. 2183-2188.

5. Holmberg S., Serzysko W., Varnauskas E. Coronary circulation during heavy exercise in control subjects and patients with coronary heart disease // Acta Medica Scandinavica. 1971. Vol. 190. № 6. P. 465-480.

6. Houghton J. L., Prisant L. M., Carr A. A. et al. Relationship of left ventricular mass to impairment of coronary vasodilator reserve in hypertensive heart disease // Am. Heart J. 1991. Vol. 121. P. 1107-1112.

7. Lang R. M., Badano L. P., Mor-Avi V. et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging // J. of Am. Society of Echocardiography. 2015. Vol. 28. № 1. P. 1-39.

8. Li W. H., Xu W. X., Li Z. P. et al. Impact of uncontrolled bloodpressure on diagnostic accuracy of coronary flow reserve for detecting significant coronary stenosis in hypertensive patients // Chinese Medical Journal. 2013. Vol. 126. № 5. P. 839-844.

9. Messer J. V., Levine H. J., Wagman R. J., Gorlin R. Effect of exercise on cardiac performance in human subjects with coronary artery disease // Circulation. 1963. Vol. 28. P. 404-414.

10. Nemes A., Forster T., Geleijnse M. L. et al. Prognostic role of aortic atherosclerosis and coronary flow reserve in patients with suspected coronary artery disease // International Journal of Cardiology. 2008. Vol. 131. № 1. P. 45-50.

11. Rigo F., Sicari R., Gherardi S. et al. The additive prognostic value of wall motion abnormalities and coronary flow reserve during dipyridamole stress echo // Eur. Heart Jour. 2008. Vol. 29. № 1. P. 79-88.

12. Sicari R., Nihoyannopoulos P., Evangelista A. et al. Stress echocardiography expert consensus statement: European Association of Echocardiography (EAE) (a registered branch of the ESC) // Eur. Jour. of Echocardiography. 2008. Vol. 9. № 4. P. 415-437.

13. Vegsundvag J., Holte E., Wiseth R. et al. Transthoracic echocardiography for imaging of the different coronary artery segments: a feasibility study // Cardiovascular Ultrasound. 2009. Vol. 7. P. 58-68.

14. Zagatina A., Zhuravskaya N. Transthoracic detection of coronary flow in left and right coronary descending arteries during supine bicycle stress echocardiography // Coronary Artery Disease. 2012. Vol. 23. P. 337-347.


Review

For citations:


Zagatina A.V., Zhuravskaya N.T., Vareldzhyan Y.P. Noninvasive assessment of coronary blood flow parameters during an exercise test in patients with arterial hypertension. Regional blood circulation and microcirculation. 2016;15(1):50-55. (In Russ.) https://doi.org/10.24884/1682-6655-2016-15-1-50-55

Views: 824


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-6655 (Print)
ISSN 2712-9756 (Online)