Dynamic of changing of the square of capillary bed during organization of myocardial infarction
https://doi.org/10.24884/1682-6655-2013-12-3-34-38
Abstract
In the article there is description of immunohistochemical investigation of microcirculatory bed of myocardium in different stages during organization of myocardial infarction. In investigation zone of necrosis, border zone and distant zones of heart were included. Description of peculiarities of expression of CD34 in experimental groups and results of statistical analysis, revealing different reaction of microcirculatory bed to formation of focus of necrosis. Also different variants of compensation during organization of acute and recurrent myocardial infarction were shown.
About the Authors
Yu. S. Korneva
Smolensk State Institute of Pathology; Smolensk State Medical Academy
Russian Federation
Russian Federation
A. E. Dorosevich
Smolensk State Institute of Pathology; Smolensk State Medical Academy
Russian Federation
Russian Federation
References
1. Салбиев К. Д. Морфогенез инфаркта миокарда у человека и в эксперименте (морфометрическое исследование): автореф. дис.. д-ра мед. наук. М., 1984. 31 с.
2. Сисакян А. С., Оганян В. А., Семерджян A. Б. и др. Влияние фактора ангиогенеза на морфофункциональное состояние миокарда у крыс при экспериментальном инфаркте миокарда // Росс. кардиолог. журн. 2004. № 2. С. 63-67.
3. Телкова И. Л., Фадеев М. В. Возможный механизм внезапной сердечной смерти при микрососудистом поражении коронарных артерий по данным аутопсии миокарда // Вестник аритмол. 2007. № 4. С. 64-67.
4. Хулуп Г. Я., Ламовская H. B. Предшественники эндотелиальных клеток: характеристика и роль в сердечнососудистой патологии // Медицина. 2008. № 4. С. 10-14.
5. Chilian W. M., Weihrauch D., Stepp D. et al. Does the coronary microcirculation play a role in heart failure? // Dialogues in Cardiovascular Medicine. 1998. Vol. 3. № 3. P. 147-158.
6. Claessen B. E., Bax M., Delewi R. et al. The Doppler flow wire in acute myocardial infarction // Heart. 2010. № 96. P. 631-635.
7. Goncalvеs L. M. Angiogenic growth factors: potential new treatment for acute myocardial infarction? // Cardiovascular Research. 2000. № 45. P. 294-302.
8. Hombach V., Grebe O., Merkle N. et al. Sequelae of acute myocardial infarction regarding cardiac structure and function and their prognostic significance as assessed by magnetic resonance imaging // Eur. Heart J. 2005. № 26. P 549-557.
9. Iliceto S. Left ventricular remodeling after acute myocardial infarction // Heart and Metabolism. 2001. № 13. Р. 2-3.
10. Scmidt-Lucke C., Rossig L., Fichtlscherer S. et al. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair // Circulation. 2005. № 111. P. 2981-2987.
11. Sun Y., Kiani M. F, Postlethwaite A. E., Weber K. T. Infarct scar as living tissue // Basic Res. Cardiol. 2002. № 97. P 343-347.
12. Weis M. Prognostic significance of microvascular dysfunction // Heart Metab. 2008. № 40. P 5-10.
Review
For citations:
Korneva Yu.S., Dorosevich A.E. Dynamic of changing of the square of capillary bed during organization of myocardial infarction. Regional blood circulation and microcirculation. 2013;12(3):34-38. (In Russ.) https://doi.org/10.24884/1682-6655-2013-12-3-34-38
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