Pathophysiological aspects of heart donation from asystolic donors
https://doi.org/10.24884/1682-6655-2020-19-4-4-11
Abstract
This article presents a view of heart transplantation from asystolic donors. Based on the recent evidence of modern research, the difficulties in heart transplantation from donors of this category are described. This article presents a classification of asystolic donors, specifies the features of each category in relation to heart donation. Based on the recent evidence of modern knowledge about asystolic donors, possible methods of assessment and management protocols for donors are presented. The article may be of interest to pathophysiologists, transplantologists, cardiologists, and medical students.
Supporting agencies: The study is supported by the grant of the Russian Scientific Foundation No 20-015-00552 А «Investigation of the mechanisms of the influence of hypothermic conditioning on the state of the myocardium and the microcirculation of the donor heart, obtained from an asystolic donor».
About the Authors
M. M. Galagudza
Pavlov University; Almazov National Medical Research Centre
Russian Federation
Russian Federation
Galagoudza Michael M. – Dr. of Sci. (Med.), professor, Director
6-8, L’va Tolstogo str., Saint Petersburg, 197022
2, Akkuratova str., Saint Petersburg, 197341
E. S. Protsak
Pavlov University; Almazov National Medical Research Centre
Russian Federation
Russian Federation
Protsak Egor S. – laboratory assistant
6-8, L’va Tolstogo str., Saint Petersburg, 197022
2, Akkuratova str., Saint Petersburg, 197341
Yu. Yu. Borschev
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Borshchev Yuri Yu. – Cand. of Sci. (Biol.), Head of the Department of toxicology
2, Akkuratova str., Saint Petersburg, Russia, 197341
S. M. Minasyan
Pavlov University; Almazov National Medical Research Centre
Russian Federation
Russian Federation
Sarkis Minasian M. – Cand. of Sci. (Med.), Senior Research Office
6-8, L’va Tolstogo str., Saint Petersburg, 197022
2, Akkuratova str., Saint Petersburg, 197341
Ya. I. Poleschenko
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Poleschenko Yana I. – resident physician
2, Akkuratova str., Saint Petersburg, Russia, 197341
A. A. Kutenkov
Pavlov University
Russian Federation
Russian Federation
Kutenkov Alexey A. – chief of surgery department
6-8, L’va Tolstogo str., Saint Petersburg, 197022
D. A. Druzhininsky
Pavlov University
Russian Federation
Russian Federation
Druzhininsky Dmitry A. – student
6-8, L’va Tolstogo str., Saint Petersburg, 197022
I. S. Uskov
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Uskov Ivan S. – junior researcher
2, Akkuratova str., Saint Petersburg, 197341
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Review
For citations:
Galagudza M.M., Protsak E.S., Borschev Yu.Yu., Minasyan S.M., Poleschenko Ya.I., Kutenkov A.A., Druzhininsky D.A., Uskov I.S. Pathophysiological aspects of heart donation from asystolic donors. Regional blood circulation and microcirculation. 2020;19(4):4-11. (In Russ.) https://doi.org/10.24884/1682-6655-2020-19-4-4-11
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