Intraperitoneal microdialysis as a method for early detection of postoperative visceral ischemia

This study presents a method of intraperitoneal microdialysis based on detection of major markers of ischemic tissue (glucose, lactate, pyruvate, glutamate, glycerol) in the extra-cellular fluid obtained intrasurgically through the intra-abdominal catheter, at the region of gastro-intestinal anastomoses. Evaluation of the biochemical substances concentration at the surgery area allows preclinical detection of possible anastomotic leakage and it also allows to determine a prevention therapy for tissue ischemia. Particularly, this work is focused on the authors' first-time experience when using intraperitoneal microdialylsis for the detection of visceral ischemia in the area of biliodigestive and pancreatodigestive anastomoses.

внутрибрюшной микродиализ, послеоперационная висцеральная ишемия, маркеры ишемии, лактат, пируват, глюкоза, несостоятельность анастомоза, intraperitoneal dialysis, postoperative visceral ischemia, ischemic markers, lactate, pyruvate, glucose, anastomotic leakage

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