Infrared fluorescence lymphography in experimental and clinical practice
https://doi.org/10.24884/1682-6655-2018-17-2-84-91
Abstract
Introduction. Near infrared (NIR) fluorescent diagnostics is promising due to a deeper penetration into biological tissues. Material and methods. In experiments on rabbits and in clinical studies evaluation the lymphatic system with the use of the instrument complex FLUM-808 was analysed. Results. For visualization of the lymphatic vessels of the skin, the intradermal administration of ICG, dissolved in 20 % albumin in the order of 0.02 mg/ml, is optimal. Peritumoral injection of ICG allows visualizing sentinel lymph nodes in patients with lung cancer. Conclusions. The developed NIR fluorescence diagnostic system FLUM-808 allows to real time visualization of lymphatic vessels and lymph nodes.
About the Authors
G. V. Papayan
Federal State Budgetary Educational Institution of Higher Education «Pavlov First Saint Petersburg State Medical University»; Federal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. L. Akopov
Federal State Budgetary Educational Institution of Higher Education «Pavlov First Saint Petersburg State Medical University»; Federal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I. I. Mechnikov»
Russian Federation
Russian Federation
P. A. Antonyan
Federal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I. I. Mechnikov»
Russian Federation
Russian Federation
A. A. Ilin
Federal State Budgetary Educational Institution of Higher Education «Pavlov First Saint Petersburg State Medical University»
Russian Federation
Russian Federation
N. N. Petrishchev
Federal State Budgetary Educational Institution of Higher Education «Pavlov First Saint Petersburg State Medical University»; Federal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Papayan G.V., Akopov A.L., Antonyan P.A., Ilin A.A., Petrishchev N.N. Infrared fluorescence lymphography in experimental and clinical practice. Regional blood circulation and microcirculation. 2018;17(2):84-91. (In Russ.) https://doi.org/10.24884/1682-6655-2018-17-2-84-91
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