Peculiarities of local blood microcirculation in patients with the psoriasis
https://doi.org/10.24884/1682-6655-2018-17-3-58-64
Abstract
The purpose of this work is to diagnose microcirculatory disorders in the tissues of psoriatic plaques in patients with psoriasis. Material and methods. Using the method of laser Doppler flowmetry (LDF), local hemodynamic parameters were studied in the place of psoriatic lesion of tissue and in uninvolved skin. Results. In the psoriatic plaque, there is an increase in average perfusion, myogenic and cardiac fluctuations, as well as nutritive blood flow as compared to the area of intact skin. Conclusions. The use of spectral analysis of the LDF signal has great potential for assessing the contribution of each link of the microvascular bed in the study the pathogenesis of psoriasis and evaluating the effectiveness of the therapy.
About the Authors
E. V. Potapova
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
M. A. Filina
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
I. O. Kozlov
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
E. V. Zharkikh
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
V. V. Dremin
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
N. S. Malaya
Orel State University named after I. S. Turgenev; Orel Regional Dermatovenereological Dispensary
Russian Federation
Russian Federation
I. A. Snimshchikova
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
A. V. Dunaev
Orel State University named after I. S. Turgenev
Russian Federation
Russian Federation
V. V. Sidorov
SPE «LAZMA» Ltd
Russian Federation
Russian Federation
A. I. Krupatkin
Priorov Central Research Institute of Traumatology and Orthopedics
Russian Federation
Russian Federation
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Review
For citations:
Potapova E.V., Filina M.A., Kozlov I.O., Zharkikh E.V., Dremin V.V., Malaya N.S., Snimshchikova I.A., Dunaev A.V., Sidorov V.V., Krupatkin A.I. Peculiarities of local blood microcirculation in patients with the psoriasis. Regional blood circulation and microcirculation. 2018;17(3):58-64. (In Russ.) https://doi.org/10.24884/1682-6655-2018-17-3-58-64
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