The state of the microcirculation of the skin in patients with pulmonary hypertension due to congenital heart defects
https://doi.org/10.24884/1682-6655-2018-17-3-65-70
Abstract
Aim - to assess the state of microcirculation in the skin in patients with pulmonary hypertension due to congenital heart defects (PH-CHD). Material and methods. The study was performed using laser Doppler flowmetry and capillaroscopy in 25 patients with PH-CHD and a control group (n=25). Results. Patients with PH-CHD have a low blood saturation of 90.1 % and 97.2 % (<0.05), a high amplitude of myogenic vasomotions of 0.49 PU and 0.26 PU (<0.05), pulsatile 0.14 PU and 0.11 PU (<0.05) and respiratory associated blood flow fluctuations of 0.24 PU and 0.13 PU (<0.05), respectively. Against this background, there is no evidence of fluid retention in the tissue. Conclusions. Changes in microcirculation are compensatory in the conditions of systemic hypoxia, caused by violations of hemodynamics in the heart and a small circle of blood circulation.
About the Authors
E. V. Dolgova
National Medical Research Center of Cargiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
A. A. Fedorovich
National Medical Research Center for Preventive Medicine of the Ministry of Healthcare of the Russian Federation; State Scientific Center of Russia Institute of Biomedical Problems of the Russian Academy of Sciences
Russian Federation
Russian Federation
T. M. Martynyuk
National Medical Research Center of Cargiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
A. N. Rogoza
National Medical Research Center of Cargiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
I. E. Chazova
National Medical Research Center of Cargiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
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For citations:
Dolgova E.V., Fedorovich A.A., Martynyuk T.M., Rogoza A.N., Chazova I.E. The state of the microcirculation of the skin in patients with pulmonary hypertension due to congenital heart defects. Regional blood circulation and microcirculation. 2018;17(3):65-70. (In Russ.) https://doi.org/10.24884/1682-6655-2018-17-3-65-70
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