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Regional blood circulation and microcirculation

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The relationship of C-reactive protein levels and clinical implications of myocardial infarction during hospital stay

https://doi.org/10.24884/1682-6655-2014-13-2-37-40

Abstract

The Multifunctional acute phase's protein - C-reactive protein (CRP) is involved in the pathogenesis of atherosclerosis. It's elevated concentrations significantly predict atherothrombotic events and consequences of myocardial infarction (MI). The aim of the work was to determine the relationship of CRP levels and clinical course of MI during in-hospital stay. Article presents data of hospital charts of 309 patients with MI treated in the St. Petersburg Research Institute for emergency medical care from January to May 2012. Patients were divided into 2 groups. The first one (I) includes 66 patients with MI and CRP level less than 5 mg/l, the second group (II) - 243 patients with CRP greater than 5 mg/l. In II group significantly more frequent Q-myocardial infarction occurred as well as postinfarction angina, recurrent myocardial infarction and heart failure. Hospital mortality among these patients was significantly higher.

About the Authors

V. A. Kostenko
Institute for Emergency Medical Care of I.I. Dzhanelidze
Russian Federation


E. A. Skorodumova
Institute for Emergency Medical Care of I.I. Dzhanelidze
Russian Federation


A. N. Fedorov
Institute for Emergency Medical Care of I.I. Dzhanelidze
Russian Federation


O. G. Kiselgof
Institute for Emergency Medical Care of I.I. Dzhanelidze
Russian Federation


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Review

For citations:


Kostenko V.A., Skorodumova E.A., Fedorov A.N., Kiselgof O.G. The relationship of C-reactive protein levels and clinical implications of myocardial infarction during hospital stay. Regional blood circulation and microcirculation. 2014;13(2):37-40. (In Russ.) https://doi.org/10.24884/1682-6655-2014-13-2-37-40

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