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Регионарное кровообращение и микроциркуляция

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Роль асимметричного диметиларгинина в патогенезе сосудистых осложнений сахарного диабета

https://doi.org/10.24884/1682-6655-2012-11-4-91-94

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Аннотация

Сахарный диабет является одним из наиболее распространенных хронических заболеваний и представляет собой серьезную проблему здравоохранения, в первую очередь, в силу развития осложнений. Развитие эндотелиальной дисфункции является одним из наиболее ранних событий в патогенезе сосудистых осложнений сахарного диабета. Асимметричный диметиларгинин (АДМА), являющийся хорошо известным маркером сердечно-сосудистого риска, может играть роль и при сахарном диабете. Результаты исследований, проведенных в последние годы, остаются противоречивыми. В данном кратком обзоре сделана попытка оценить взаимосвязь уровня АДМА с развитием эндотелиальной дисфункции и сосудистых осложнений при сахарном диабете.

Об авторах

Е. Н. Кравчук
Федеральный центр сердца, крови и эндокринологии им. В. А. Алмазова
Россия


М. М. Галагудза
Федеральный центр сердца, крови и эндокринологии им. В. А. Алмазова; Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова
Россия


А. А. Карпов
Федеральный центр сердца, крови и эндокринологии им. В. А. Алмазова
Россия


А. В. Федоров
Федеральный центр сердца, крови и эндокринологии им. В. А. Алмазова
Россия


Р. Н. Родионов
Технологический Университет Дрездена
Россия


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Для цитирования:


Кравчук Е.Н., Галагудза М.М., Карпов А.А., Федоров А.В., Родионов Р.Н. Роль асимметричного диметиларгинина в патогенезе сосудистых осложнений сахарного диабета. Регионарное кровообращение и микроциркуляция. 2012;11(4):91-94. https://doi.org/10.24884/1682-6655-2012-11-4-91-94

For citation:


Kravchuk E.N., Galagudza M.M., Karpov A.A., Fedorov A.V., Rodionov R.N. The role of asymmetric dimethylarginine in the pathogenesis of vascular disease in diabetes mellitus. Regional blood circulation and microcirculation. 2012;11(4):91-94. (In Russ.) https://doi.org/10.24884/1682-6655-2012-11-4-91-94

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