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Predictors of myocardial reperfusion syndrome: a modern view of the issue and current problems. Part 1: Reperfusion arrhythmias, injury and stunning myocardium (review of literature)

https://doi.org/10.24884/1682-6655-2021-20-2-20-26

Abstract

Myocardial reperfusion syndrome is a complex set of pathological processes that occur in the heart muscle due to restoration of coronary blood flow in patients with ST-segment elevation myocardial infarction. Despite the fact that it has been known for a long time, there is still no unequivocal opinion about the predictors, and, accordingly, the risk groups for its occurrence. This prevents predicting the further course of the disease and studying the effectiveness of surgical and therapeutic methods for preventing the consequences of reperfusion in patients with ST-segment elevation myocardial infarction, which in turn significantly worsens the postoperative and long-term prognosis in this group of patients. We used the search engines such as E-lilbrary, Google Scholar and Pubmed to search for studies on this issue. The article presents research data highlighting predictors of myocardial reperfusion syndrome. In addition, the problems of verification of irreversible reperfusion injury and myocardial stunning are described.

About the Authors

G. G. Khubulava
Military Medical Academy
Russian Federation

Khubulava Gennady G. – MD, Professor, Academician the Russian Academy of Sciences, Head of the Departmentand Clinic of Surgery (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



K. L. Kozlov
Military Medical Academy
Russian Federation

Kozlov Kirill L. – MD, professor, professor of the Departmentand Clinic of Surgery (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



A. N. Shishkevich
Military Medical Academy
Russian Federation

Shishkevich Andrey N. – MD, head of the X-ray surgical department of the Surgery Clinic (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



S. S. Mikhailov
Military Medical Academy
Russian Federation

Mikhaylov Sergey S. – Ph. D., senior resident of the X-ray surgery department of Surgery Clinic (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



E. Yu. Bessonov
Military Medical Academy
Russian Federation

Bessonov Evgeny Yu. – resident of the X-ray surgical department of the Surgery Clinic (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



D. A. Pachkov
Military Medical Academy
Russian Federation

Pachkov Dmitry A. – anesthesiologist-resuscitator of the Surgery Clinic (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



E. I. Umancev
Military Medical Academy
Russian Federation

Umantsev Evgeny I. – X-ray surgeon of the Surgery Clinic (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



A. Ya. Khandokhov
Military Medical Academy
Russian Federation

Khandokhov Aslan Ya. – X-ray surgeon of the Surgery Clinic (Improvements of Doctors) №1 

6 Academiva Lebedeva street, Saint Petersburg, 194044



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Review

For citations:


Khubulava G.G., Kozlov K.L., Shishkevich A.N., Mikhailov S.S., Bessonov E.Yu., Pachkov D.A., Umancev E.I., Khandokhov A.Ya. Predictors of myocardial reperfusion syndrome: a modern view of the issue and current problems. Part 1: Reperfusion arrhythmias, injury and stunning myocardium (review of literature). Regional blood circulation and microcirculation. 2021;20(2):20-26. (In Russ.) https://doi.org/10.24884/1682-6655-2021-20-2-20-26

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