Gender specifics remodeling suprarenal and infrarenal aortic in hypertension

Introduction and aim. Hypertension leads to vascular remodeling, due to change its geometry and functional properties. The aim of the study was to investigate of gender specifics of the remodeling of suprarenal and infrarenal parts of the abdominal aorta in hypertension. Materials and Methods. A total of 147 patients (76 men and 71 women aged 35-68 years) with normal blood pressure and hypertension 1-3 degree based in the trial. Using duplex sonography was studied by changing of the diameter and of the wall thickness of the suprarenal and infrarenal aorta. Using tissue Doppler imaging has been evaluated time and velocities values of the front and back walls motion of the aorta. Results and discussion. The values of systolic - diastolic increase of the diameter and the thickness of the wall of the abdominal aorta, Young's incremental elastic modulus, circumferential wall stress, the peak velocities of the front and back walls motion of suprarenal and infrarenal aorta are obtained in the surveyed categories of persons based on sexual differences of the indicators analyzed characteristics. Conclusions. The remodeling of the suprarenal and infrarenal aorta begins in the men at an arterial hypertension of the 2nd degree and is manifested by increased stiffness, circumferential walls stress and reduce velocities values of the front and back walls motion of the aorta. Thickening of the walls of the abdominal aorta in men is an adaptive re-sponse to increase of the wall stress, begins in the men at an arterial hypertension hypertension of the 3rd degree, later than women. Therefore, the risk of the aortic dissection is above in men in the hypertension. The suprarenal aorta is practically not susceptible to pathological remodeling in the women in the increase of the blood pressure Opposite, at an arterial hypertension of the 2nd degree the thickening of the walls of the infrarenal aorta reduces the risk of the aortic dissection in the early stages of hypertension.

супраренальный, инфраренальный отдел аорты, ремоделирование, артериальная гипертензия, suprarenal, infrarenal aorta, remodeling, arterial hypertension

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